Nath Mala (Ms) - Department of Chemistry,Indian Institute of Technology Roorkee
Nath Mala (Ms)
Mala Nath Emeritus professor mala.nath@cy.iitr.ac.in 91-01332-285797
Areas of Interest
  • Organotin/organosilicon chemistry, Organotin-based anti-cancer compounds and their mode of action, Organotin chemistry, Organotin compounds as precursors for nanosized sem-conducting SnO2, Metal-organic frameworks, Metal-organic based Materials of multi-functional utility
Professional Background
FromPeriodPositionOrganisation
2001-01-01OngoingPROFESSORINDIAN INSTITUTE OF TECHNOLOGY ROORKEE
1988-01-0113 years ASSOCIATE PROFESSORUNIVERSITY OF ROORKEE
1994-01-014 years READER/ASST. PROF.UNIVERSITY OF ROORKEE
Multiple Posts
FromPeriodPositionOrganisation
2006-01-012 years Departmental representative of research comitteeIITR
2015-01-01OngoingMemberIAPC
2016-01-01OngoingPresiding OfficerInternal Complaints Committee
2008-01-012 years Coordinator for ChemistryIIT Mandi
2015-01-012 years Chairperson, DAPCDepartment of Chemistry
2008-01-012 years Member of library committeeIITR
2008-01-012 years OC LIBRARYIITR
2013-01-01Chairperson of M.Tech. admissionIITR
2014-01-01Chairperson of M.Tech. admissionat IITR
2015-01-01Chairperson of M.Tech. AdmissionIITR
2016-01-01Chairperson, M.Tech. AdmissionIITRoorkee
2002-01-018 years Member of Professorial committee of Biotechnology DepartmentIITRoorkee
Honors and Awards
AwardInstituteYear
Two Gold medals for Ist position in M.Sc.Lucknow university, Lucknow1976
one Gold medal for Ist position in B.Sc.Navyug Kanya Vidyalaya, Lucknow University1974
Educational Details
DegreeSubjectUniversityYear
B.Sc.Chemistry, Botany, Zoology with Ist Position Lucknow University, Lucknow 1974
B.Sc. HonsInorganic Chemistry with 2nd positionLucknow University, Lucknow 1975
M.Sc.Inorganic Chemistry with Ist positionLucknow University, Lucknow 1976
Ph.D.Organotellurium ChemistryLucknow University, Lucknow 1980
Sponsored Research Projects
TopicFunding AgencyStart DatePeriod
Organotin(IV) Carboxylates and their mixed Ligands Comds. as Chemotherapeutics and their mechanismDBT2018-01Ongoing
NMR Structural and Biophysical Studies on binding of anthraquinone derivatives with Guanine-QuadruplDBT, New Delhi2017-01Ongoing
QSAR and solution studies of organotin- peptides/nucleotidesDepartment of Science and Technology, New Delhi2005-0115 years 7 months
Hydrogen storage using activated carbon based materials incorporated with metal-organic compoundsMHRD2011-019 years 7 months
New organotin derivatives of amino acids and peptides:Synthesis,characterization, antitumor activityUGC1998-0122 years 7 months
Synthesis, structural and biological activity of organotin compoundsCouncil of Science & Technology, U.P., Lucknow2002-0118 years 7 months
Synthesis,structural and biological studies on organometallic compounds ofSi, Sn and Pb of S-ligandsCSIR1994-0126 years 7 months
Extraction and determination of Mo, Pd and Pt by using Schiff basesUniversity grants commission2004-0116 years 7 months
Studies on Reactivity of metal and organometal complexesof Schiff Bases of amino acidsCouncil of Science & Technology, U.P., Lucknow1989-0131 years 7 months
Role of transition metals in chemical evolutionDST, New Delhi1990-0130 years 7 months
Participation in seminars
NamePlaceSponsored ByDate
Seminar on Organometallic Chemistry (dedicated to Late Prof. T. N. Srivastava)Lucknow UniversityLucknow University/ DST New Delhi2020-08
Memberships
  • American Chemical Society, Member
  • National Science Congress, Life member
  • National Academy of Sciences India, Allahabad , Member
  • National Academy of Sciences India, Dehradun , Member
  • Indian Chemical Society, Kolcutta, Life member
Teaching Engagements
TitleCourse CodeClass NameSemester
Common ChemistryCy-101B.Tech. First YearAutumn
General Chemistry-IICY-006B.Tech. First YearSpring
Advanced Coordination Chemistry Revised courseCYN-509M.Sc. Autumn
PracticalsCYN-511M.Sc. Autumn
Solid state chemistry and its applicationsCYN-611M.Sc. Autumn
Organometallic chemistry and Inorganic rings, chains and clustersCYN-502M.Sc. Spring
Chemistry for B. Tech. I YrCYN-008B.Tech. I YrSpring
Advanced Coordination Chemistry (New revised ccourse in 2016)CYN-509M.Sc. First YearAutumn
ORGANOMETAALIC CHEMISTRY, INORGANIC RINGS, CHAINS AND CLUSTERSCYN-502M.Sc. First YearSpring
Advanced Laboratory-ICY-561M.Sc. First Year + Intg. M.Sc. IV YearAutumn
Advanced Laboratory-ICYN-511M.Sc. First Yr. + Intg. M.Sc. IV Yr,Autumn
Advanced Coordination ChemistryCYN-509M.Sc. First Yr. + Intg. M.Sc. IV Yr,Autumn
Basic Inorganic ChemistryCy-512M.Sc. First Year +Intg. M. Sc. IV YearSpring
Advanced Organometallic ChemistryCYN-502M.Sc. First Yr. + Intg. M.Sc. IV Yr,Spring
Advanced Coordination and Organometallic ChemistryCY-512M.Sc. First Year + Intg. M.Sc. IV YearSpring
Coordination Chemistry (old no:CY-551)CYN-509M.Sc. First Year + Intg. M.Sc. IV YearAutumn
Advanced Coordination Chemistry (old course)CY-631M.Sc.Second YearAutumn
LAB ICY-551M.Sc. First Year + Intg. M.Sc. IV YearAutumn
LAB IICY-542M.Sc. First Year + Intg. M.Sc. IV YearSpring
Solid-state Chemistry and its applicationCY-643M.Sc.Second Year + Intg. M.Sc. V YearAutumn
Advanced Inorganic Chemistry ICY-622M.Sc.Second YearSpring
Advanced Inorganic Chemistry (I)CY-622(I)M.Sc.Second YearSpring
Specialised PracticalsCY-641M.Sc.Second YearAutumn
Solid State Chemistry and its applicationsCYN-622(I)M.Sc. Second Year + Intg. M.Sc. V Yr.Autumn
Projects and Thesis Supervised
Title of ProjectNames of Students
Preparation and characterization of carbonaceous materials incorporatedwith organometallic compoundsSh. Asheesh Kumar
Studies on Organosilicon(IV) Derivatives of Schiff Bases Ms. Deepti Arora
Organosilicon Derivatives of Oxygen and Nitrogen Donor LigandsSh. Sanjay Kumar Maurya
PHDs Supervised
TopicScholar NameStatus of PHDRegistration Date
Organotin(IV) Complexes of Macromolecular N-DonorsSh. Sundeep KumarO2011-01
Interaction of Organotin(IV) moities with DrugMs. RanjanaO2013-01
Speciation, Cytotoxic and DNA Binding Studies of Organotin(IV) CarboxylatesMs. MridulaO2010-01
Interaction of Organotin(IV) Moities with DNA and Nucleic Acid ConstitutentsMs. Nagamani KompelliO2009-01
Organotin(IV) Carboxylates: Potential Anti-tumor and Anti-inflammatory Agents Ms. Monika VatsO2007-01
Stabilization of Cubic Spinel Li-Mn-O by Dopants,As Cathode Material in Li-ion BatteryMs. Priti Singh O2006-01
Organotin(IV) Derivatives of Schiff Bases andMacrocyclesSh. Permendra Singh SainiO2003-01
Organotin(IV) Derivatives of Peptides andNucleotides.Sh. Hitendra SinghO2002-01
Organotin Derivatives of Some Heterocyclic LigandsMs. SulaxnaO2001-01
Studies on Novel Organotin(IV) Derivatives of PeptidesSh. Sandeep PokhariaO1999-01
Interaction of Organotin(IV) Compounds with Biologically Important LigandsMs. Ruchi JairathO2000-01
Studies on Organosilicon(IV) Derivatives ofAmino AcidsMs. Sunita GoyalO1996-01
Studies on Organotin(IV) Derivatives of Amino Acids and DipeptidesMs. Rakesh YadavO1995-01
Preparation and Characterization of Some Rare-Earth(III)-Iron(III) Mixed OxidesMs. Nidhi BhartiO1992-01
Studies of Organotin(IV) Complexes of ThioSchiff BasesMs. Savita GoyalO1990-01
Role of Ferrocyanide in Chemical Evolution Ms. Archana SharmaO1987-01
Physiochemical Studies of Organotin Schiff Bases ComplexesMs. Neelam SharmaO1987-01
Chemical Evolution of Transition metal (Fe, Zn) contg. Enzymes Ms. S. W. DeopuzariO1984-01
Metal-Organic Frame works as Adsorbents and PhotocatalystsRamesh ChandraO2014-01
Metal Sulphide Nanoparticles@Metal-organic Frameworks: As PhotocatalystSh. Ankur MallickO2015-01
Metal Oxides/Sulphides base Nano Composites and their ApplicationsPooja BhatiaO2016-01
Organotin complexes as catalysts in organic synthesisShubhamO2017-01
Organotin derivatives of O- and N- donors as green catalysts and PVC stabilizersVinod YadavO2018-01
Visits to outside institutions
Institute VisitedPurpose of VisitDate
NIT Uttarakhand, Srinagar1. To frame Chemistry courses (02) for B. Tech. I and II year students and Pre-Ph. D. courses (04) in Chemistry. 2.Invited Guest Lecture on “Cancer Chemotherapy: Challenges and Future Perspectives of Metal Based Drugs” followed by the interactive sessio2020-08-04
Punjab University, Chandigargh, IndiaDelivered an invited lecture on "Developments of Organotin Compounds as Chemotherapeutic Agents: Challenges and Future prospects" in Achievements of Women in Science and Technology: Current Scenario and Future Prospects-2017, held on 13-14 Jan.,2017 at Pu2020-08-04
-To present a research paper entitled 'Core-Shell Based SnO2NPs@ZIF-8Compositeas an Effective Photo-catalystfor Degradation of Methylene Blue in Wastewater Treatment' in 9th International Conference on Materials for Advanced Technologies (ICMAT-2017) at Su2020-08-04
-To present a research paper, entitled 'Temperature Cntrolled Single Phase TiO2 (Anatase/Rutile) Nanoparticles by Using Metal-Organic Compounds as Precursors in 11th Asian Thermophysical Properties Conference, ATPC-2016, HELD ON 2-6 October, 2016 at Yokoha2016-01-01
University of Exeter, UKAttended and presented a paper entitled, "Production of Semicon-ductors Nanometric Particles of SnO2 and SnS from Organo-tin(IV) Triazolates as Precursors", in "International Conference on Condensed Matter and Materials Physics (Sym2020-08-04
-To present a research paper, entitled 'Metal-based Anticancer Agents: In Vitro DNA Binding, Cleavage and Cytotoxicity' in International Conference on Metallurgy, Materials Science and Engineering: ICMMSE-2014 held on 14-15 August 2014 at NH Laguna Palac2020-08-04
University of Mauritius, Mauritius1. Delivered a plenary lecture on "Developments in Organotin-based Anti-tumor Compounds" in International Conference on Pure and Applied Chemistry. 2. Attended and Presented a research paper entitled, "Spectral Characterization and Anticancer Screening o2020-08-04
University of LucknowDelivered an Invited Lecture on, “Developments and Mode of Action of Organotin-based Anti-Cancer Compounds” in International Conference & Humboldt Kolleg on “ Recent Aspects of Organic/ Organometallic Compounds and their Usefulness in Materials and Indu2020-08-04
University of MexicoAttended and Presented a research paper entitled, "Microporous Carbonaceous Materials Incorporated with Metal (TI, V and Zn) for Hydrogen Storage" in ", XXI International Materials Reasearch Congress (XXI IMRC)".2020-08-04
NIT HamirpurTo conduct Ph. D. Viva-voce2015-01-01
University of LucknowDelivered an Invited Lecture on, “Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory Agents”in a Seminar organized on ‘Organometallic Chemistry’ (dedicated to Late Prof. T. N. Srivastava). 2020-08-04
Invitations
TopicOrganistaionDate
Developments in Organotin-based Anti-cancer CompoundsUniversity of Mauritius (in: International Conference on Pure and Applied Chemistry (ICPAC-2010)) 2010-01
Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory AgentsLucknow University (Seminar on ‘Organometallic Chemistry')2010-01
Developments and Mode of Action of Organotin-based Anti-Cancer CompoundsLucknow University (in:International Conference “ Recent Aspects of organometallics")2012-01
" Developments of Organotin Compounds as Chemotherapeutic Agents: Challenges and Future Prospects" (In: Achievements of Women in Science and Technology: Current Scenario and Future Prospects)-2017Punjab University, Chandigarh, India2017-01
To design the syllabii of Pre-Ph.D. courses of chemistry department and B.Tech I and II Yr. Chemistry Courses (2018)NIT, Srinagar, Garhwal2018-01
Courses or Conferences Organised
Conference NameSponsored ByDate
Gender Sensitization and Sexual Harassment of Women at WorkplaceIIT Roorkee2020-08
Special Lectures Delivered
TitlePlaceDate
Cancer Chemotherapy: Challenges and Future Perspectives of Metal Based DrugsNIT Uttarakhand, Srinagar2020-08
Challenges and Future Prospects of Metal-based Drugs in Cancer Chemotherapy (2018)NIT Srinagar, Garhwal2018-01
International Conference on Pure and Applied Chemistry.Maurtius2020-08
Organotin(IV) Compounds: Anti-cancer and Anti-inflammatory AgentsLucknow University, Lucknow2020-08
DEVELOPMENT AND MODE OF ACTION OF ORGANOTIN-BASED ANTI-CANCER COMPOUNDSUniversity of Lucknow, Lucknow2020-08
Instructional tasks - 1. The students are asked to solve the assignments in the class. 2. The students do/practice the problems based on GATE/CSIR-UGC NET in class.
Particulars of course - 1. Laboratory Manual for B.Tech. I Yr Course, CYN-006, CYN-008 Under QIP program of 2013-2014. 2. Laboratory Manual for M. Sc. I Yr Course, CYN-551, CYN-510 Under QIP program of 2014-2015.
Innovation in teaching - 1. Design the practicals of B.Tech. I Yr, Revised courses CYN-006, CYN-008 in such a way to impart the practical training of various important aspects of chemistry to complete it with in 2 hr of practical class. 2. Teaching the students through power point with suitable graphics software to show actual 3d- structure to the students. 3. Assignments at postgraduate level have been designed to cover the format/types of questions asked in GATE/CSIR-UGC NET examinations.
Books Authored

1. Inorganic Chemistry: A Laboratory Manual, Published by Narosa Publishing House Pvt. Ltd., New Delhi,  India, 2016.

2. Book Chapter, entitled "The Cardiovascular Activity of Organotin Compounds" in:Tin Chemistry, Fundamentals, Frontiers, and Applications, Eds.: A.G. Davies, M. Gielen, K.H. Pannell, E.R.T. Tiekink, Published by Wiley, A John Wiley and Sons, Ltd, Publication,2008.

Refereed Journal Papers

1. Multifunctional CdSNPs@ZIF-8: Potential Antibacterial Agent against GFP-Expressing Escherichia coli and Staphylococcus aureus and Efficient Photocatalyst for Degradation of Methylene Blue, A. Malik, Mala Nath, S. Mohiyuddin and G. Packirisamy, ACS Omega, 3 (2018) 8288-8308.

2Structure-cytotoxicity Relationship for Apoptotic Inducers Organotin(IV) Derivatives of Mandelic Acid and L-Proline and their Mixed Ligand Complexes having Enhanced Cytotoxicity, Mala Nath, P. Roy, R Mishra and M. ThakurAppl. Organomet. Chem. (2018), e4663; DOI: 10.1002/aoc.4663.

3. New diorganotin(IV) complexes of salicylaldehyde based hydrazones bearing furan heterocycle moiety:X-ray structural investigation of dimethyltin(IV) and diphenyl-tin(IV) complexes.Sundeep Kumar and Mala Nath, J. Organomet. Chem., 856 (2018) 87-99.

4.Synthesis, Characterization and Binding Studies of Novel Diorganotin(IV) Complexes of Sodium 2-mercaptoethane-sulfonate. Ranjana Kumari and Mala Nath*, Appl. Organomet. Chem. (2018), DOI: 10.1002/aoc.4365.

5. Synthesis and Characterization of Novel Trimethyltin(IV) and Tributylltin(IV) Complexes of Anticoagulant, WARFARIN: Potential DNA Binding and Plasmid Cleaving Agents, R. Kumari and Mala Nath, Inorg. Chem. Commun., 95 (2018) 40-46.

6. Tri- and diorganotin(IV) derivatives of non-steroidal anti-inflammatory  drug, Sulindac: Characterization, electronic structures (DFT), DNA binding, and plasmid cleavage studies. Ranjana Kumari and Mala Nath*, Appl. Organomet. Chem. (2017),       doi/10.1002/aoc.e- 3661.

7. Novel Binuclear diorganotin(IV) complexes of adipic acid dihydrazone containing  flexible aliphatic spacer: X-ray structural characterization of dimethyltin(IV) complex.Sundeep Kumar and Mala Nath, J. Organomet. Chem., 853 (2017) 113-121.

8.Microwave–assisted synthesis of mixed ligands organotin(IV) complexes of 1,10-phenanthroline and L-proline: physicochemical characterization, DFT calculations,chemotherapeutic potential validation by in vitro DNA binding and nuclease activity. Mala Nath*, Mridula and Ranjana Kumari, J. Photochem. Photobiol. B: Biology, 174 (2017) 182-194.

9. New triphenyltin(IV) complexes of flexible tripodal Schiff base ligands: X-ray structural characterization of Ph3SnCl. (H3trensal). Sundeep Kumar and Mala Nath, J. Organomet. Chem., 848 (2017) 10-21. 

10.Multi-Core–shell TiO2NPs@ZIF-8 Composite for Enhanced Photocatalytic Degradation and Adsorption of Methylene Blue and Rhodamine-B,R. Chandra, Mala NathChem. Select., 2 (2017) 7711-7722.

11. TiO2@ZIF-8: A Novel Approach of Modifying Micro-environment for Enhanced Photo-catalytic Dye Ddegradation and High Usability of TiO2 Nanoparticles. R. Chandra, S. Mukhopadhyay, M. Nath, Mat. Lett. `164 (2016) 571-574.

12. Conventional and Microwave–assisted Synthesis, Characterization, DFT Calcula-tions, in vitro DNA Binding and Cleavage Studies of Potential Chemotherapeutic Diorganotin(IV) Mandelates. Mridula and Mala Nath*, J. Photochem. Photobiol. B: Biology, 162 (2016) 348-360.

13. Mode of Action of Tin-based Anti-proliferative Agents: Biological Studies of Organotin(IV) Derivatives of Fatty Acids, M. Nath  M. Vats, P. Roy, J. Photo-chem. Pho-tobiol. B: Biology, 148 (2015) 88-100.

14. Tri- and diorganotin(IV) complexes of biologically important orotic acid: Synthesis,spectroscopic studies, in vitro anti-cancer, DNA fragmentation, enzyme assays and in vivo anti-inflammatory activities, M. Nath , M. Vats  and P. Roy, Eur. J. of Med. Chem., 59 (2013) 310-321.

15. Chemistry and applications of organotin(IV) complexes of Schiff bases. Perspective, M. Nath and P. K. Saini, Dalton Trans 40 (2011), 7077-7121.

16.. Design and Microwave-assisted Synthesis of Tri- and Dialkyltin(IV) Hippurates, Characterization, In Vitro Anti-cancer and In Vivo Anti-inflammatory Activities, M. Nath, M. Vats, P. Roy, Med. Chem. Res.,24 (2015) 51-62.

17.. Design, Spectral Characterization, Anti-tumor and Anti-inflammatory Activity of Triorganotin(IV) Hydroxyl-carboxylates, Apoptosis Inducers: In Vitro Assessment of Induction of Apoptosis by Enzyme, DNA-fragmentation, Acridine Orange and Comet Assays,M. NathM. Vats, P. Roy, Inorg. Chim. Acta, 423 (2014) 70-82.

18..New di- and triorganotin(IV) complexes of tripodal Schiff base ligand containing three imidazole arms: Synthesis, structural characterization, biological activity and thermal studies, M. Nath, P. K. Saini and A. Kumar, J. Organomet. Chem., 695 (2010), 1353–1362.

19. Organotin(IV)tryptophanylglycinates: Potential Non-Steroidal Anti-inflammatory  Agents; Crystal Structure of Dibutyltin(IV) tryptophanylglycinate, M. Nath, H. Singh, P. Kumar, A. Kumar, X. Song and G. Eng, Appl. Organomet. Chem., 23 (2009), 347-358.

20.. New Triorganotin(IV) Derivatives of Dipeptides as Anti-inflammatory Anti-microbial Agents, M. Nath S.  Pokharia,  G.  Eng,  X.  Song, and  A. Kumar,  Eur.  J.  Med. Chem., 40(3), (2005), 289-298.

21Preparation and Characterization of Li[Mn2-xFex]O4 (x = 0.0-0.6) Spinel Nanoparticles as Cathode Materials for Lithium Ion Battery, P. Singh, A. Sil, M. Nath, S. Ray, Adv. Mater. Res., 67 (2009) 233-238.

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